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The Broad Institute Interview Questions

The questions to prepare for The Broad Institute interviews, across all roles. Questions from real interview reports rank first. Updated weekly.

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1
CodingStart here. 5 questions · ~49 min
2
Execution5 questions · ~49 min
3
Machine Learning4 questions · ~39 min
Supervised vs Unsupervised LearningEasy

Explain how supervised and unsupervised learning differ, and ground the distinction in a practical ML example.

Unsupervised LearningFeature EngineeringBias-Variance TradeoffThe Broad Institute
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4
Product Sense5 questions · ~49 min
Designing for Accessibility at ScaleMedium

Approach for building accessibility into product design through user needs, research, use cases, and measurable outcomes.

User NeedsPain PointsUse CasesThe Broad Institute
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5
Metrics5 questions · ~49 min
Diagnose a Metric Drop After LaunchMedium

Investigate why a key KPI moved the wrong way after a product change and separate signal from noise.

Lagging IndicatorsLeading IndicatorsDiagnosisThe Broad Institute
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6
Pipelines4 questions · ~39 min
Monitoring Tools for Data PipelinesEasy

Preferred tools and approach for monitoring and managing data pipelines in production.

InfrastructureToolsQualityThe Broad Institute
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7
More topics22 questions · ~217 min
Pitfalls in Streaming Experiment AnalysisHard

Identify major online experiment pitfalls and explain how they can bias results in a streaming product A/B test.

Network InterferenceNovelty EffectSample Ratio MismatchThe Broad Institute
Determining A/B Test SignificanceMedium

Explain how to evaluate whether an A/B test result is statistically significant and how to interpret the result.

marketing experimentStatistical SignificanceAnalysisThe Broad Institute
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Hands-on SQL practiceWrite and run real queries in the editor. 3 drills · ~30 min
The finish line: interview-readyComplete all 50 questions plus 3 hands-on drills to finish this plan.