Tempus AI is a technology company advancing precision medicine through the practical application of artificial intelligence in healthcare. As a Data Analyst—often aligned with clinical trials or clinical data management—you sit at the intersection of molecular biology, oncology data, and software engineering. Your work directly enables physicians to make real-time, data-driven decisions for cancer patients and helps pharmaceutical partners accelerate clinical trials.

The role is highly critical because clinical data is notoriously unstructured, messy, and complex. By cataloging, processing, and analyzing diverse datasets—ranging from genomic profiles to longitudinal clinical outcomes—you help build the foundation of the Tempus AI library. This library is used by researchers to discover novel therapeutic insights and match patients to life-saving clinical trials.

This position offers a unique opportunity to apply analytical skills directly to the frontlines of cancer research. While the work requires intense focus and rigorous attention to detail, the potential to impact patient lives makes it an exceptionally rewarding path for analysts with a passion for healthcare and life sciences.

The following questions are representative of what candidates face during the Tempus AI interview process. They are drawn from actual candidate experiences and are categorized to help you identify patterns in how the hiring team evaluates analytical and behavioral competency.

Clinical Data Manipulation & Excel Cases

• Given a raw dataset of oncology patients, how would you structure and catalog their symptoms and treatment timelines in Excel?
• How do you ensure data integrity when merging clinical trial datasets from different source systems?
• Walk me through how you handled the clinical data analysis take-home project, and explain your categorization choices.

Preparing for an interview at Tempus AI requires a blend of clinical domain awareness, technical precision, and behavioral adaptability. You should focus on demonstrating how your analytical skills translate into highly accurate, structured data products that support clinical decision-making.

Clinical Domain Aptitude – Candidates must show a strong grasp of clinical terminology, trial structures, or oncology concepts. Tempus AI values analysts who can look at raw patient histories and understand the underlying medical context without constant supervision.

Rigorous Attention to Detail – Because clinical data impacts patient outcomes and research validity, errors are costly. Interviewers look for methodical approaches to data cleaning, cataloging, and validation.

Resilience & Execution Speed – The environment at Tempus AI is fast-paced and high-volume. Showing that you can maintain accuracy under pressure and manage repetitive data-structuring tasks efficiently is key to succeeding here.

Cross-Functional Communication – You must be able to translate complex data findings into clear, actionable insights for clinical data managers, software engineers, and directors.

The interview process for a Data Analyst at Tempus AI typically begins with an initial phone screening with a recruiter, followed by a conversation with the hiring manager or a team supervisor. A core component of the evaluation is a take-home clinical data assessment, designed to simulate the day-to-day responsibilities of the role. This project usually involves cataloging, cleaning, or structuring sample patient datasets (often related to cancer symptoms or clinical trials) within a set timeframe.

Following successful submission of the assessment, you will progress to a series of virtual or panel interviews. This stage often consists of multiple back-to-back 30-minute sessions with clinical data managers, team supervisors, and directors. While the process is designed to be thorough and conversational, candidates should prepare for potential variability in communication speed and timeline lengths, as historical feedback indicates the scheduling and decision-making phases can sometimes stretch over several weeks.

This visual timeline outlines the typical progression from the initial recruiter screen to the intensive final panel rounds. Candidates should use this roadmap to pace their preparation, ensuring they allocate sufficient time to complete the clinical take-home project, which is a critical gateway to the final interviews.

Clinical Data Structuring & Curation

This is the most critical technical evaluation area for the Data Analyst role at Tempus AI. You will be assessed on your ability to ingest messy, unstructured clinical data—such as patient symptoms, treatment regimens, and oncology histories—and transform it into a highly structured, standardized format. The hiring team wants to see how you categorize complex medical information accurately and systematically.

Be ready to go over:

• Data Cataloging Standards – Understanding how to map diverse clinical terms to unified definitions or databases.
• Oncology & Clinical Trial Concepts – Familiarity with how patient symptoms, drug interventions, and therapeutic responses are documented.
• Excel Data Organization – Utilizing lookup functions, data validation, and logical formatting to present clean, structured clinical profiles.

Advanced concepts (less common):

• Knowledge of standard clinical vocabularies (e.g., ICD-10, MedDRA, SNOMED CT).
• Basic understanding of genomic data integration with clinical histories.

Example scenarios:

• "You are given a raw PDF of patient clinical notes. Walk us through your methodology for extracting and cataloging key symptom onset dates and treatment outcomes into a structured spreadsheet."
• "How would you resolve discrepancies when two different medical records provide conflicting dates for a patient's diagnosis?"

Technical Execution & Analytical Tools

While the role is highly clinical, you must demonstrate strong proficiency with fundamental data analysis tools. Depending on the specific team, this may range from advanced Excel workflows to structured SQL queries or basic coding challenges. The focus is on your ability to manipulate data efficiently without sacrificing accuracy.

Be ready to go over:

• Advanced Excel Functions – Mastery of VLOOKUP/XLOOKUP, INDEX-MATCH, nested IF statements, and pivot tables.
• SQL Querying Basics – Writing queries to filter, join, and aggregate datasets from relational databases.
• Data Quality Auditing – Identifying outliers, missing values, and formatting inconsistencies in large datasets.

Advanced concepts (less common):

• Basic scripting in Python or R for automating repetitive data cleaning tasks.
• Live coding or query-writing under time constraints during technical interviews.

Example scenarios:

• "Write a SQL query to identify all patients in a database who have been diagnosed with a specific cancer subtype and have undergone more than two rounds of therapy."
• "Explain how you would automate the validation of a weekly clinical data import to flag missing dosage values."

Behavioral Resilience & Mission Alignment

Tempus AI operates in a high-stakes, rapidly evolving industry where the workload can be intense. Interviewers actively assess your work ethic, your ability to handle repetitive or mundane data tasks, and your alignment with the company's mission to leverage data for cancer care. They want to ensure you are motivated by the patient impact of your work and can thrive in a fast-paced environment.

Be ready to go over:

• Managing Repetitive Tasks – Demonstrating a positive, methodical approach to high-volume data curation.
• Handling Ambiguity – Navigating situations where data guidelines are unclear or evolving.
• Workload Management – Prioritizing tasks effectively when managing multiple clinical datasets simultaneously.

Example scenarios:

• "The process of cataloging clinical data can sometimes feel highly repetitive. What motivates you to maintain a high level of accuracy and focus during these tasks?"
• "Describe a time when you had to adapt quickly to a major change in project requirements or data guidelines mid-way through an analysis."

A Data Analyst at Tempus AI is primarily responsible for the curation, standardization, and quality control of clinical datasets that power the company's precision medicine platform. On a day-to-day basis, you will review unstructured clinical records, molecular data, and clinical trial documents to extract, validate, and catalog critical patient information. This structured data is vital for clinical trial matching, therapeutic research, and guiding real-time physician decisions.

In this role, you will collaborate closely with Clinical Data Managers, Software Engineers, and Product Teams to ensure that the data pipelines are seamless and accurate. You will participate in defining data curation guidelines, auditing existing databases for inconsistencies, and identifying opportunities to streamline the data ingestion process. Your work directly impacts the reliability of the clinical insights that Tempus AI delivers to healthcare providers and life sciences partners.

To be competitive for the Data Analyst position at Tempus AI, candidates must demonstrate a strong blend of clinical curiosity and technical execution.

• Must-have skills:

  • Strong proficiency in Excel (including pivot tables, complex formulas, and data cleaning techniques).
  • Solid understanding of SQL for data querying, filtering, and aggregation.
  • Exceptional attention to detail and a methodical approach to data verification.
  • A background or strong interest in life sciences, biology, public health, or clinical research.

• Nice-to-have skills:

  • Basic programming skills in Python or R for data manipulation.
  • Experience working with clinical trial registries, electronic health records (EHR), or medical coding standards.
  • Prior experience in an oncology or bioinformatics research environment.