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Tempus AISoftware Engineer
Updated · Reviewed by the Dataford team

Tempus AI Software Engineer interview questions & guide 2026

Every question Tempus AI interviewers actually ask, the frameworks that win the room, and the language hiring managers respond to.

4 rounds · ≈ 3-5 weeks
1
Recruiter Screen
2
Online Technical Assessment
3
Hiring Manager Screen
4
Multi-Stage Virtual Onsite

What is a Software Engineer at Tempus AI?

A Software Engineer at Tempus AI sits at the critical intersection of technology, data science, and precision medicine. The company's mission is to gather, structure, and analyze clinical and genomic data to help physicians make real-time, data-driven decisions for cancer care and other therapeutic areas. In this role, you will be responsible for building the scalable platforms, robust APIs, and data pipelines that make this massive library of clinical data accessible and actionable.

The impact of your work in this position is direct and profound. By writing clean, efficient, and highly secure code, you enable healthcare providers to match patients with personalized clinical trials and targeted therapies. You will work on sophisticated systems that handle complex genomic sequencing data, natural language processing tools to extract insights from unstructured clinical notes, and user-facing applications utilized by thousands of oncologists daily.

This is a fast-paced, mission-driven engineering environment where technical rigor meets medical innovation. Teams at Tempus AI operate with high autonomy, requiring engineers who are not only technically excellent but also deeply curious about the domain space. Whether you are optimizing a database query to search through millions of records or designing a secure microservice, your contributions directly accelerate the pace of clinical discovery.

Common Interview Questions

Preparing for the technical and conversational aspects of the loop is essential to demonstrating your capabilities. The questions asked during the Tempus AI interview process are highly practical, focusing on database manipulation, API development, clean coding practices, and behavioral alignment. While your specific questions will depend on the team and seniority level, they consistently follow distinct patterns designed to evaluate your real-world engineering skills.

Coding & Algorithms

These questions evaluate your fundamental computer science knowledge, data structure selection, and code correctness. Interviewers care deeply about code accuracy and your ability to write clean, bug-free logic under a time constraint.

  • Write a function to calculate the TF-IDF (Term Frequency-Inverse Document Frequency) score for a set of clinical documents.
  • Given a string of brackets and characters, determine if the input string is valid and correctly balanced.

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03 · Question bank

The questions most likely to come up

Sorted by relevance to this company
Top Tests Per Department QueryMedium
Tests your ability to write SQL using ranking or aggregation patterns for analytics.
Window FunctionsRankingAggregations
Dynamic Text Pattern GeneratorEasy
Tests your ability to implement correct logic for parameterized output and edge cases.
javascriptloopsbasics
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Getting Ready for Your Interviews

Success at Tempus AI requires a balanced preparation strategy that covers core computer science fundamentals, practical system building, and behavioral readiness. You should approach your preparation with a focus on writing clean, production-ready code and demonstrating a strong interest in the company's healthcare mission.

Technical Correctness & Accuracy – During the coding challenges and live programming sessions, your interviewers will evaluate the correctness of your solution above all else. Ensure you write clean code, handle edge cases systematically, and thoroughly test your logic before declaring a problem solved.

Practical System Design – You must be ready to design practical, real-world services rather than highly theoretical architectures. Focus on REST API design, database schemas, microservices communication, and the trade-offs between SQL and NoSQL databases in a healthcare data context.

Mission Alignment & AgilityTempus AI operates in a highly regulated yet rapidly evolving industry. Show that you are comfortable with ambiguity, capable of learning complex scientific concepts, and motivated by the prospect of improving patient outcomes through software engineering.

Interview Process Overview

The interview loop for a Software Engineer is designed to test both your immediate coding capabilities and your long-term architectural thinking. The process moves quickly, often initiating within days of your application, and demands consistent performance across both automated and live evaluation stages.

The process begins with an initial recruiter screen, followed by a rigorous online technical assessment. If you pass the assessment, you will move to a hiring manager screen or go directly to a multi-stage virtual onsite interview. Tempus AI places a strong emphasis on practical coding and system design, meaning you will spend the majority of your interview time writing code, designing APIs, and discussing system architecture with senior engineers.

06 · The loop

The interview process, end to end

≈ 3-5 weeks · 4 rounds
1
Recruiter Screen

Initial screening call with a recruiter to assess your fit for the role.

2
Online Technical Assessment

Rigorous online assessment testing coding capabilities, serving as a critical gatekeeper.

3
Hiring Manager Screen

Discussion with the hiring manager to evaluate your qualifications and fit for the team.

4
Multi-Stage Virtual Onsite

Series of virtual interviews focusing on coding, API design, and system architecture.

The visual timeline above outlines the typical progression of the software engineering interview loop from the initial touchpoint to the final decision. Candidates should use this sequence to pace their preparation, ensuring they master the online assessment requirements before shifting focus to system design and architectural deep dives. While the stages are standardized, individual teams may adjust the technical focus of the onsite rounds based on the specific engineering stack.

Deep Dive into Evaluation Areas

Online Assessment & Codility

The online assessment is your first technical hurdle and is typically hosted on platforms like Codility. It is designed to filter for solid programming fundamentals and strong SQL querying skills.

You will face a timed, multi-question test that usually consists of algorithmic challenges and a dedicated SQL problem. Unlike other tech companies that focus purely on LeetCode algorithms, Tempus AI heavily evaluates your ability to manipulate data using SQL.

Be ready to go over:

  • SQL Aggregations and Joins – Writing multi-table joins, using window functions, and filtering complex datasets.
  • Data Structure Manipulation – Efficiently using arrays, hash maps, and strings to solve algorithmic problems.
  • Language-Specific Implementations – Solving coding challenges using languages like JavaScript or Python depending on the test requirements.

Example scenarios:

  • Writing a SQL query to identify patient cohorts who have undergone specific treatments within a precise timeframe.
  • Implementing an algorithm to parse and validate complex clinical data strings.

Live Coding & Pair Programming

The live coding round is a collaborative session with two engineering team members. It focuses on your ability to build functional, clean, and maintainable software components rather than solving abstract riddles.

During this hour, you will write code in a shared environment. You may be asked to build a small web service, implement REST API endpoints, or write interactive frontend components. The interviewers will observe your coding style, your familiarity with modern frameworks, and how you structure your code.

Be ready to go over:

  • REST API Development – Setting up routes, handling HTTP requests, and returning structured JSON data using frameworks like Express or FastAPI.
  • Asynchronous Programming – Managing asynchronous operations, promises, and API integrations smoothly.
  • React Components – Creating functional, stateful UI components that interact with backend services.
  • Advanced concepts
    • Middleware integration for authentication and logging.
    • Error handling and input validation in web frameworks.

Example scenarios:

  • Building a basic Express server with endpoints to create, read, update, and delete patient records.
  • Creating a React component that fetches data from a mock API and displays it in a searchable table.

System Design & Architecture

The system design session evaluates your ability to architect scalable, resilient, and secure software systems. This is a conversational interview where you will lead the whiteboarding or diagramming process.

You will design a system from scratch, discussing data models, network protocols, caching strategies, and service boundaries. Because Tempus AI handles sensitive healthcare data, incorporating security, data privacy, and compliance considerations into your design will highly differentiate your performance.

Be ready to go over:

  • Data Modeling – Choosing between relational databases and NoSQL solutions for complex clinical and genomic data.
  • Scalability and Performance – Implementing caching layers, load balancers, and message queues to handle high-traffic volumes.
  • API Design – Designing clean, versioned, and secure APIs for internal and external consumption.
  • Advanced concepts
    • Microservices communication patterns (gRPC vs. REST vs. Event-driven).
    • Data compliance and security architectures (HIPAA, encryption at rest and in transit).

Example scenarios:

  • Designing a system that ingests, processes, and stores genomic sequencing data from multiple external laboratories.
  • Architecting a secure, high-throughput API gateway that handles authentication and rate limiting for healthcare providers.

Behavioral & Product Alignment

The behavioral rounds assess your soft skills, your collaboration style, and how you align with the fast-paced, mission-driven culture at Tempus AI. You will speak with product managers, engineering leads, and directors.

Interviewers want to see that you can communicate complex technical ideas to non-technical stakeholders, adapt to changing product requirements, and work effectively within cross-functional teams. They will also explore your career motivations and your genuine interest in the intersection of healthcare and technology.

Be ready to go over:

  • Cross-Functional Collaboration – How you partner with product managers, QA, and data scientists to deliver features.
  • Conflict Resolution – Navigating technical disagreements and reaching a consensus with your team.
  • Prioritization and Delivery – Managing your time and deliverables when faced with tight deadlines or shifting requirements.

Example scenarios:

  • Describing a situation where you had to make a technical compromise to meet a critical product launch deadline.
  • Sharing an experience where you had to explain a complex technical limitation to a product manager and propose an alternative solution.
08 · Topic breakdown

What they actually test for

Topic distribution
All topics
Coding interviews (timed exercises)JavaScriptSystem designAlgorithms & data structuresSQL

Key Responsibilities

As a Software Engineer at Tempus AI, your day-to-day work will directly impact the company's core data platforms and clinical applications. You will be responsible for the entire software development lifecycle, from initial system design and data modeling to deployment, monitoring, and maintenance.

You will write clean, well-tested, and performant code in a highly collaborative environment. Your daily routine will include close partnership with product managers to define feature requirements, data scientists to integrate machine learning models, and security teams to ensure strict compliance with healthcare regulations.

Additionally, you will actively contribute to the engineering culture by participating in code reviews, mentoring junior engineers, and continuously improving development workflows. You will design APIs that power internal research tools and external clinical portals, ensuring that high-quality patient data is delivered securely and instantly to those who need it most.

Role Requirements & Qualifications

To be competitive for a Software Engineer position at Tempus AI, you must demonstrate strong technical capabilities alongside excellent problem-solving and communication skills. The hiring team looks for candidates who possess a solid foundation in modern software engineering practices and are eager to apply their skills to complex healthcare challenges.

  • Must-have skills
    • Strong proficiency in modern programming languages such as JavaScript/TypeScript, Python, Go, or Java.
    • Solid understanding of SQL and experience writing complex queries and optimizing database performance.
    • Experience designing, building, and maintaining robust RESTful APIs and microservices.
    • Familiarity with modern cloud platforms (such as AWS or GCP) and containerization tools like Docker.
  • Nice-to-have skills
    • Experience with modern frontend frameworks, particularly React, and Node.js-based backend frameworks.
    • Prior background in healthcare tech, bioinformatics, or working with regulated datasets (HIPAA compliance).
    • Experience with distributed data processing systems or large-scale data pipelines.
  • Soft skills
    • Outstanding communication and the ability to explain technical concepts to cross-functional partners.
    • A proactive, self-motivated approach to solving ambiguous problems in a fast-paced environment.
    • Strong alignment with the company's mission to leverage data and AI to improve patient care.

Frequently Asked Questions

Q: How difficult is the Software Engineer interview process at Tempus AI? A: Candidates generally describe the process as average to difficult. The technical standards are high, particularly regarding SQL proficiency and code correctness during the online assessment. However, the questions themselves are practical and representative of real-world engineering challenges rather than highly abstract algorithms.

Q: Can I choose my preferred programming language for the coding interviews? A: For the online assessment, you can typically choose from a variety of standard languages. However, for live coding rounds, some teams may require or strongly prefer that you use specific technologies like JavaScript/Node.js or Python, depending on the stack of the team you are interviewing for. It is best to clarify this with your recruiter before the onsite.

Q: How long does the entire interview process take from start to finish? A: The typical timeline spans 3 to 4 weeks. Tempus AI recruiters are often very quick to initiate the process, but scheduling multiple rounds of virtual onsite interviews with busy engineering leads can sometimes introduce delays.

Q: What is the work culture like for software engineers at the company? A: The engineering culture is fast-paced, highly collaborative, and deeply mission-driven. Teams operate with a high level of ownership, which means you will have the opportunity to make a significant impact quickly, but you must also be comfortable navigating shifting priorities and fast product iterations.

Other General Tips

To maximize your chances of success during the Tempus AI recruitment process, keep these practical, insider tips in mind:

  • Master SQL Querying: Do not underestimate the database portion of the evaluation. Brush up on complex joins, aggregations, window functions, and indexing strategies, as SQL is a core component of the initial online assessment.
  • Be Prepared for JavaScript Specifics: If you are interviewing for a full-stack or frontend-heavy role, expect deep-dive questions on JavaScript quirks, asynchronous behavior, and React state management. Ensure you are comfortable writing functional JS code without relying on external libraries.
  • Communicate Your Architectural Trade-offs: During the system design interview, do not just present a single solution. Discuss the pros and cons of your design decisions, such as choosing SQL over NoSQL, or synchronous APIs over event-driven architectures, particularly in the context of scaling healthcare data.
  • Connect with the Mission: Tempus AI is deeply committed to precision medicine. Take time to understand their products, their data-driven approach to oncology, and be ready to articulate why you want to apply your engineering skills to this specific domain space.

Summary & Next Steps

The Software Engineer position at Tempus AI offers a unique opportunity to build high-impact software that directly contributes to the advancement of cancer research and precision medicine. The work is technically challenging, intellectually stimulating, and highly rewarding for engineers who want their code to make a tangible difference in people's lives.

To succeed in this competitive interview process, focus your preparation on solidifying your SQL skills, mastering core coding fundamentals, and designing scalable, practical web architectures. Additionally, prepare to demonstrate your adaptability, collaborative spirit, and strong alignment with the company's fast-paced, mission-driven environment.

14 · Compensation

What this role pays

8 reports
USUSD
Estimated total compLow confidence · 8 data points
$0k-$0k
Median $130k / year
Base salary · 100%Stock (RSU) · 0%Cash bonus · 0%
25thEntry / smaller markets
$78k
50thTypical offer
$130k
90thTop performers / major metros
$182k
Breakdown by component
Base salary
100% of total
$89k$155k
$122k
median
Stock (RSU)
0% of total
$0$0
$0
median
Cash bonus
0% of total
$0$0
$0
median
Aggregated from 8 self-reported salaries via Glassdoor. Estimates only. Verify against your offer.

The salary ranges shown above reflect the competitive compensation packages offered by Tempus AI for engineering roles in major hubs like Chicago. When preparing your compensation expectations, consider how your specific technical expertise, years of experience, and performance throughout the interview loop align with these established ranges.

With focused preparation and a clear understanding of the evaluation criteria, you can navigate the interview loop with confidence. For more detailed interview insights, company profiles, and preparation resources, explore additional interview insights and resources on Dataford to help you land your next engineering role.

17 · FAQ

Tempus AI Software Engineer interview FAQ

Answered from real candidate and compensation data
How many rounds is the Tempus AI Software Engineer interview process?
Candidates report 4 stages: Recruiter Screen, Online Technical Assessment, Hiring Manager Screen, and Multi-Stage Virtual Onsite. The interview process section above breaks down what each stage covers.
How much does a Software Engineer at Tempus AI make?
Reported compensation for Software Engineer roles at Tempus AI ranges from roughly $89k base to $182k total per year, varying by level, team, and location.
What topics come up in the Tempus AI Software Engineer interview?
Tempus AI Software Engineer interviews most often cover Coding interviews (timed exercises), JavaScript, System design, Algorithms & data structures, and SQL, based on topics extracted from real candidate reports.
What questions does Tempus AI ask Software Engineer candidates?
Recent candidates report questions like "Top Tests Per Department Query" and "Dynamic Text Pattern Generator". The question bank above tracks 20 questions for this role, ranked by how often they come up in Tempus AI interviews.