Top 45
Prep plan
Updated weekly · Last refresh Oct 17

Caris Life Sciences Data Scientist Interview Questions

The questions to prepare for a Caris Life Sciences Data Scientist interview. Questions from real interview reports rank first. Updated daily.

45questions
~6htotal time
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1
SQL & Data ManipulationStart here. 4 questions + 2 drills · ~53 min
2
Machine Learning8 questions · ~67 min
Handling Severe Class ImbalanceMedium

Explain how to train and evaluate a classifier when the positive class is rare and accuracy is misleading.

ExperimentationFeature EngineeringSupervised LearningCaris Life Sciences
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3
A/B Testing & Experimentation6 questions · ~50 min
Use CUPED to Improve Experiment PowerHard

Assess how CUPED changes variance and sample size in an online experiment, and decide whether the uplift is detectable.

ExperimentationCUPEDPower AnalysisCaris Life Sciences
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4
Model Evaluation3 questions · ~25 min
Common Model Evaluation MetricsEasy

Explain common machine learning evaluation metrics and when each is useful.

PrecisionAccuracyRecallCaris Life Sciences
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5
Statistics & Probability5 questions · ~42 min
Explaining P Values ClearlyEasy

Explain what a p-value means, how it relates to statistical significance, and how to describe it clearly to non-technical stakeholders.

CommunicationStatistical SignificanceP-ValuesCaris Life Sciences
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6
Product Sense4 questions · ~33 min
Define Metrics for New FeaturesMedium

Define a success metric for a new feature that captures real user value, not just raw usage.

MetricsFeature Prioritizationuser valueCaris Life Sciences
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7
More topics15 questions · ~125 min
Diagnose KPI Drop After ReleaseMedium

Diagnose a post-release KPI drop by separating instrumentation issues from real behavior changes and tracing the problem through the metric hierarchy.

KPILeading IndicatorsDiagnosisCaris Life Sciences
Cold Start and Feature DriftHard

Tests system design for maintaining recommendation quality over time in clinical settings.

Cold StartFeature StoreFeature DriftCaris Life Sciences
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The finish line: interview-readyComplete all 45 questions plus 2 hands-on drills to finish this plan.