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Updated weekly · Last refresh Nov 6

BigHat Biosciences Data Scientist Interview Questions

The questions to prepare for a BigHat Biosciences Data Scientist interview. Questions from real interview reports rank first. Updated daily.

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1
System DesignStart here. 1 question · ~8 min
End-to-End ML System DesignHard

Evaluates your system-level thinking for building and validating an ML solution end to end.

case studyBigHat Biosciences
2
Statistics & Probability2 questions · ~16 min
Key Considerations for RNA-SeqHard

Assesses your ability to handle RNA-seq data pitfalls and analysis considerations.

experimental designBigHat Biosciences
Linear Mixed Effects ModelsHard

Tests your understanding of mixed effects modeling and its core assumptions.

assumptionsBigHat Biosciences

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3
SQL & Data Manipulation1 question + 3 drills · ~38 min
Databases You’ve UsedEasy

Tests your practical SQL and data storage knowledge relevant to research pipelines.

JoinsData WranglingAggregationsBigHat Biosciences
Using Data to Solve ProblemsMedium
Practice
Practice drill

Use campaign data to compare conversion performance and demonstrate a data-driven answer with PostgreSQL.

JoinsData Analysisbusiness problemMicrosoft
Analyzing Nursing Data with SQLHard
Practice
Practice drill

Analyze CMS nursing staffing records by facility, handling missing data and classifying facilities against a staffing benchmark.

JoinsData Analysiscase studyClipboard Health
Optimize a Slow SQL QueryHard
Practice
Practice drill

Rewrite a slow PostgreSQL loan payment query to reduce scanned rows while preserving the required aggregated results.

database optimizationJoinsData WranglingBiz2CreditAmeripriseEEltro Cyberchrome Private
4
Pipelines1 question · ~8 min
Build a Scientific Data PipelineMedium

Evaluates your ability to design and implement data pipelines for scientific analysis.

data processingBigHat Biosciences
5
Machine Learning1 question · ~8 min
Principal Component Analysis BasicsMedium

Tests foundational knowledge of dimensionality reduction techniques.

BigHat Biosciences
6
A/B Testing & Experimentation1 question · ~8 min
Improve Experimental Design and AnalysisMedium

Assesses experimental reasoning and your approach to analyzing and refining study design.

experimental designData AnalysisBigHat Biosciences
7
Behavioral & Leadership2 questions · ~16 min
Reflect on a Past Project ChangeMedium

Assesses reflective thinking and how you improve your work over time.

BigHat Biosciences
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The finish line: interview-readyComplete all 9 questions plus 3 hands-on drills to finish this plan.