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Denali Therapeutics Data Analyst Interview Questions

The questions to prepare for a Denali Therapeutics Data Analyst interview. Questions from real interview reports rank first. Updated daily.

3questions
~1htotal time
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1
SQL & Data ManipulationStart here. 1 question + 3 drills · ~38 min
Analyzing Missing Values in Clinical DataMedium

Explain how to profile, quantify, and handle missing values in joined clinical datasets using SQL.

Data WranglingCase WhenAggregationsDenali Therapeutics
Handling Missing DataEasy
Practice
Practice drill

Replace missing sales fields with defined defaults and return a consistently ordered dataset.

missing valuesdata cleaningnull handlingUniversity of MinnesotaThe Home DepotNationwide
Average Reels Watch Time with NULLsEasy
Practice
Practice drill

Compute average Instagram Reels watch time by surface, excluding NULL values with AVG and GROUP BY.

Data WranglingCase WhenAggregationsMeta
SQL to Flag Partner Count MismatchesMedium
Practice
Practice drill

Compare partner-reported and internal daily counts, then flag discrepancies and show the prior comparison status.

JoinsData WranglingCase WhenGoogle
2
Pipelines1 question · ~8 min
Optimize a Pipeline BottleneckMedium

Explain how you identified and fixed a bottleneck in a data pipeline while preserving correctness and operational visibility.

data processingperformancebottleneck optimizationDenali Therapeutics

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3
Behavioral & Leadership1 question · ~8 min
Hands-On Technical BackgroundMedium

Assesses depth of hands-on technical experience for the Data Analyst role.

technical backgroundexperienceDenali Therapeutics
The finish line: interview-readyComplete all 3 questions plus 3 hands-on drills to finish this plan.